The role of focal adhesion anchoring domains of CAS in mechanotransduction

CAS is a docking protein, which was shown to act as a mechanosensor in focal adhesions. The unique assembly of structural domains in CAS is important for its function as a mechanosensor. The tension within focal adhesions is transmitted to a stretchable substrate domain of CAS by focal adhesion-targ...

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Published in:Sci Rep
Main Authors: Braniš, Jaroslav, Pataki, Csilla, Spörrer, Marina, Gerum, Richard C., Mainka, Astrid, Cermak, Vladimir, Goldmann, Wolfgang H., Fabry, Ben, Brabek, Jan, Rosel, Daniel
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390273/
https://ncbi.nlm.nih.gov/pubmed/28406229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46233
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