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Human dihydrofolate reductase gene is located in chromosome 5 and is unlinked to the related pseudogenes.

The chromosomal location of the human dihydrofolate reductase (DHFR; EC 1.5.1.3) gene that is amplified in a methotrexate-resistant human cell line has been investigated by screening a large number of human-mouse cell hybrids containing overlapping subsets of human chromosomes. A correlation of geno...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Maurer, B J, Barker, P E, Masters, J N, Ruddle, F H, Attardi, G
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1984
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344861/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6584893/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.5.1484
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