Human dihydrofolate reductase gene is located in chromosome 5 and is unlinked to the related pseudogenes.

The chromosomal location of the human dihydrofolate reductase (DHFR; EC 1.5.1.3) gene that is amplified in a methotrexate-resistant human cell line has been investigated by screening a large number of human-mouse cell hybrids containing overlapping subsets of human chromosomes. A correlation of geno...

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Bibliographic Details
Main Authors: Maurer, B J, Barker, P E, Masters, J N, Ruddle, F H, Attardi, G
Format: Artigo
Language:Inglês
Published: 1984
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC344861/
https://ncbi.nlm.nih.gov/pubmed/6584893
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