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Anti-Inflammatory and Cardioprotective Effects of Tadalafil in Diabetic Mice
BACKGROUND: Insulin resistance impairs nitric oxide (NO) bioavailability and obesity promotes a state of chronic inflammation and damages the vascular endothelium. Phosphodiesterase-5 inhibitors restore NO signaling and may reduce circulating inflammatory markers, and improve metabolic parameters th...
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| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448606/ https://ncbi.nlm.nih.gov/pubmed/23028874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045243 |
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