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Crystal Structure of Human Enterovirus 71

Enterovirus 71 is a picornavirus associated with fatal neurological illness in infants and young children. Here we report the crystal structure of enterovirus 71 and show that, unlike in other enteroviruses, the “pocket factor”, a small molecule that stabilizes the virus, is partly exposed on the fl...

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Autors principals: Plevka, Pavel, Perera, Rushika, Cardosa, Jane, Kuhn, Richard J., Rossmann, Michael G.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448362/
https://ncbi.nlm.nih.gov/pubmed/22383808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1218713
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