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Neutralizing antibodies can initiate genome release from human enterovirus 71

Antibodies were prepared by immunizing mice with empty, immature particles of human enterovirus 71 (EV71), a picornavirus that causes severe neurological disease in young children. The capsid structure of these empty particles is different from that of the mature virus and is similar to “A” particle...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Plevka, Pavel, Lim, Pei-Yin, Perera, Rushika, Cardosa, Jane, Suksatu, Ampa, Kuhn, Richard J., Rossmann, Michael G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926013/
https://ncbi.nlm.nih.gov/pubmed/24469789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320624111
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