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Neutralizing antibodies can initiate genome release from human enterovirus 71

Antibodies were prepared by immunizing mice with empty, immature particles of human enterovirus 71 (EV71), a picornavirus that causes severe neurological disease in young children. The capsid structure of these empty particles is different from that of the mature virus and is similar to “A” particle...

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Detalhes bibliográficos
Main Authors: Plevka, Pavel, Lim, Pei-Yin, Perera, Rushika, Cardosa, Jane, Suksatu, Ampa, Kuhn, Richard J., Rossmann, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926013/
https://ncbi.nlm.nih.gov/pubmed/24469789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320624111
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