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Structure of human enterovirus 71 in complex with a capsid-binding inhibitor

Human enterovirus 71 is a picornavirus causing hand, foot, and mouth disease that may progress to fatal encephalitis in infants and small children. As of now, no cure is available for enterovirus 71 infections. Small molecule inhibitors binding into a hydrophobic pocket within capsid viral protein 1...

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Detalhes bibliográficos
Principais autores: Plevka, Pavel, Perera, Rushika, Yap, Moh Lan, Cardosa, Jane, Kuhn, Richard J., Rossmann, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619292/
https://ncbi.nlm.nih.gov/pubmed/23509286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222379110
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