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Structure of human enterovirus 71 in complex with a capsid-binding inhibitor

Human enterovirus 71 is a picornavirus causing hand, foot, and mouth disease that may progress to fatal encephalitis in infants and small children. As of now, no cure is available for enterovirus 71 infections. Small molecule inhibitors binding into a hydrophobic pocket within capsid viral protein 1...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Plevka, Pavel, Perera, Rushika, Yap, Moh Lan, Cardosa, Jane, Kuhn, Richard J., Rossmann, Michael G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619292/
https://ncbi.nlm.nih.gov/pubmed/23509286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222379110
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