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Structure of human enterovirus 71 in complex with a capsid-binding inhibitor

Human enterovirus 71 is a picornavirus causing hand, foot, and mouth disease that may progress to fatal encephalitis in infants and small children. As of now, no cure is available for enterovirus 71 infections. Small molecule inhibitors binding into a hydrophobic pocket within capsid viral protein 1...

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Detaylı Bibliyografya
Asıl Yazarlar: Plevka, Pavel, Perera, Rushika, Yap, Moh Lan, Cardosa, Jane, Kuhn, Richard J., Rossmann, Michael G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619292/
https://ncbi.nlm.nih.gov/pubmed/23509286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222379110
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