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Lymphoid Priming in Human Bone Marrow Begins Prior to CD10 Expression with Up-Regulation of L-selectin

The expression of CD10 has long been used to define human lymphoid commitment. We report a unique lymphoid-primed population in human bone marrow that was generated from hematopoietic stem cells (HSCs) before the onset of CD10 expression and B cell commitment. This subset was identified by high expr...

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Bibliografske podrobnosti
Main Authors: Kohn, Lisa A., Hao, Qian-Lin, Sasidharan, Rajkumar, Parekh, Chintan, Ge, Shundi, Zhu, Yuhua, Mikkola, Hanna K.A., Crooks, Gay M.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448017/
https://ncbi.nlm.nih.gov/pubmed/22941246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2405
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