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Nanoscale structure and dynamics of ABOBEC3G complexes with single-stranded DNA
The DNA cytosine deaminase APOBEC3G (A3G) is capable of blocking retrovirus replication by editing viral cDNA and impairing reverse transcription. However, the biophysical details of this host-pathogen interaction are unclear. Here we applied atomic force microscopy (AFM) and hybrid DNA substrates t...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448016/ https://ncbi.nlm.nih.gov/pubmed/22809226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300733d |
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