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Enzymes for the Homeland Defense: Optimizing Phosphotriesterase for the Hydrolysis of Organophosphate Nerve Agents()

Phosphotriesterase (PTE) from soil bacteria is known for its ability to catalyze the detoxification of organophosphate pesticides and chemical warfare agents. Most of the organophosphate chemical warfare agents are a mixture of two stereoisomers at the phosphorus center and the S(P)-enantiomers are...

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Bibliographic Details
Main Authors: Tsai, Ping-Chuan, Fox, Nicholas, Bigley, Andrew N., Harvey, Steven P., Barondeau, David P., Raushel, Frank M.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447986/
https://ncbi.nlm.nih.gov/pubmed/22809162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300811t
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