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Stereoselective Hydrolysis of Organophosphate Nerve Agents by the Bacterial Phosphotriesterase

Organophosphorus compounds include many synthetic, neurotoxic substances that are commonly used as insecticides. The toxicity of these compounds is due to their ability to inhibit the enzyme acetylcholine esterase. Some of the most toxic organophosphates have been adapted for use as chemical warfare...

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Autors principals: Tsai, Ping-Chuan, Bigley, Andrew, Li, Yingchun, Ghanem, Eman, Cadieux, C. Linn, Kasten, Shane A., Reeves, Tony E., Cerasoli, Douglas M., Raushel, Frank M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945820/
https://ncbi.nlm.nih.gov/pubmed/20701311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101056m
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