IL-15 Augments TCR-Induced CD4(+) T Cell Expansion In Vitro by Inhibiting the Suppressive Function of CD25(High) CD4(+) T Cells

Due to its critical role in NK cell differentiation and CD8(+) T cell homeostasis, the importance of IL-15 is more firmly established for cytolytic effectors of the immune system than for CD4(+) T cells. The increased levels of IL-15 found in several CD4(+) T cell-driven (auto-) immune diseases prom...

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Autores principales: Van Belle, Tom L., Dooms, Hans, Boonefaes, Tom, Wei, Xiao-Qing, Leclercq, Georges, Grooten, Johan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447928/
https://ncbi.nlm.nih.gov/pubmed/23028916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045299
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