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Defects in Mitochondrial Fission Protein Dynamin-Related Protein 1 Are Linked to Apoptotic Resistance and Autophagy in a Lung Cancer Model

Evasion of apoptosis is implicated in almost all aspects of cancer progression, as well as treatment resistance. In this study, resistance to apoptosis was identified in tumorigenic lung epithelial (A549) cells as a consequence of defects in mitochondrial and autophagic function. Mitochondrial funct...

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Bibliografski detalji
Glavni autori: Thomas, Kelly Jean, Jacobson, Marty R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447926/
https://ncbi.nlm.nih.gov/pubmed/23028930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045319
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