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Exercise training decreases activation of the mitochondrial fission protein dynamin-related protein-1 in insulin-resistant human skeletal muscle

Defects in mitochondrial dynamics, the processes of fission, fusion, and mitochondrial autophagy, may contribute to metabolic disease including type 2 diabetes. Dynamin-related protein-1 (Drp1) is a GTPase protein that plays a central role in mitochondrial fission. We hypothesized that aerobic exerc...

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Detalhes bibliográficos
Main Authors: Fealy, Ciaran E., Mulya, Anny, Lai, Nicola, Kirwan, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122691/
https://ncbi.nlm.nih.gov/pubmed/24947026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01064.2013
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