Mitochondrial Utilization of Competing Fuels Is Altered in Insulin Resistant Skeletal Muscle of Non-obese Rats (Goto-Kakizaki)

AIM: Insulin-resistant skeletal muscle is characterized by metabolic inflexibility with associated alterations in substrate selection, mediated by peroxisome-proliferator activated receptor δ (PPARδ). Although it is established that PPARδ contributes to the alteration of energy metabolism, it is not...

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Publicat a:Front Physiol
Autors principals: Lai, Nicola, Fealy, Ciarán E., Kummitha, Chinna M., Cabras, Silvia, Kirwan, John P., Hoppel, Charles L.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308651/
https://ncbi.nlm.nih.gov/pubmed/32612543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00677
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