GLP-1 Receptor Antagonist Exendin-(9-39) Elevates Fasting Blood Glucose Levels in Congenital Hyperinsulinism Owing to Inactivating Mutations in the ATP-Sensitive K(+) Channel

Infants with congenital hyperinsulinism owing to inactivating mutations in the K(ATP) channel (K(ATP)HI) who are unresponsive to medical therapy will require pancreatectomy to control the hypoglycemia. In preclinical studies, we showed that the GLP-1 receptor antagonist exendin-(9-39) suppresses ins...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Calabria, Andrew C., Li, Changhong, Gallagher, Paul R., Stanley, Charles A., De León, Diva D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Diabetes Association 2012
Gaiak:
Pathophysiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447900/
https://ncbi.nlm.nih.gov/pubmed/22855730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0166
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