Motif-Optimized Subtype A HIV Envelope-based DNA Vaccines Rapidly Elicit Neutralizing Antibodies When Delivered Sequentially

HIV-1 infection results in the development of a diverging quasispecies unique to each infected individual. Envelope (Env)-specific neutralizing antibodies (NAbs) typically develop over months to years after infection and initially are limited to the infecting virus. In some subjects, antibody respon...

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Autori principali: Pissani, Franco, Malherbe, Delphine C., Robins, Harlan, DeFilippis, Victor R., Park, Byung, Sellhorn, George, Stamatatos, Leonidas, Overbaugh, Julie, Haigwood, Nancy L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447634/
https://ncbi.nlm.nih.gov/pubmed/22749601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.06.042
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