Induction of mouse metallothionein-I mRNA by bacterial endotoxin is independent of metals and glucocorticoid hormones.

++Induction of metallothionein-I (MT-I) mRNA by bacterial endotoxin (LPS) was examined. A single injection of LPS induced MT-I mRNA accumulation in both liver and kidney comparable to that induced by heavy metals. Maximal message levels were achieved 6 hr after LPS administration, prior to any incre...

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Bibliographic Details
Main Authors: Durnam, D M, Hoffman, J S, Quaife, C J, Benditt, E P, Chen, H Y, Brinster, R L, Palmiter, R D
Format: Artigo
Language:Inglês
Published: 1984
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC344762/
https://ncbi.nlm.nih.gov/pubmed/6322185
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