Amplification of the metallothionein-I gene in cadmium-resistant mouse cells.

Friend leukemia cells resistant to cadmium toxicity were selected. More than 70% of total cysteine incorporation in these cells was into the metal-binding protein, metallothionein. We used cDNA and genomic DNA clones containing the metallothionein-I gene to measure the concentration of its mRNA, the...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Beach, L R, Palmiter, R D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319293/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6941274/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2110
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