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Design, Synthesis, and Antitumor Evaluation of Novel Pyrazolo[3,4-d]pyrimidine Derivatives

A new series of pyrazolo[3,4-d]pyrimidines has been synthesized. The new compounds were tested for their antitumor activity on 60 different cell lines, and some of the compounds were found to have potent antitumor activity. In particular, 2-hydroxybenzaldehyde [1-(4-chlorophenyl)-3-methyl-1H-pyrazol...

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Detalhes bibliográficos
Main Authors: Kandeel, Manal M., Mohamed, Lamia W., Abd El Hamid, Mohammed K., Negmeldin, Ahmed T.
Formato: Artigo
Idioma:Inglês
Publicado em: Österreichische Apotheker-Verlagsgesellschaft 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447607/
https://ncbi.nlm.nih.gov/pubmed/23008804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1204-23
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