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Design, Synthesis, and Antitumor Evaluation of Novel Pyrazolo[3,4-d]pyrimidine Derivatives

A new series of pyrazolo[3,4-d]pyrimidines has been synthesized. The new compounds were tested for their antitumor activity on 60 different cell lines, and some of the compounds were found to have potent antitumor activity. In particular, 2-hydroxybenzaldehyde [1-(4-chlorophenyl)-3-methyl-1H-pyrazol...

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Autori principali: Kandeel, Manal M., Mohamed, Lamia W., Abd El Hamid, Mohammed K., Negmeldin, Ahmed T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Österreichische Apotheker-Verlagsgesellschaft 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447607/
https://ncbi.nlm.nih.gov/pubmed/23008804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1204-23
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