Clinically Employed Opioid Analgesics Produce Antinociception via μ-δ Opioid Receptor Heteromers in Rhesus Monkeys

[Image: see text] Morphine and related drugs are widely employed as analgesics despite the side effects associated with their use. Although morphine is thought to mediate analgesia through mu opioid receptors, delta opioid receptors have been implicated in mediating some side effects such as toleran...

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Hauptverfasser: Yekkirala, Ajay S., Banks, Matthew L., Lunzer, Mary M., Negus, Stevens S., Rice, Kenner C., Portoghese, Philip S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2012
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447399/
https://ncbi.nlm.nih.gov/pubmed/23019498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300049m
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