Mutations M287L and Q266I in the Glycine Receptor α1 Subunit Change Sensitivity to Volatile Anesthetics in Oocytes and Neurons, but Not the Minimal Alveolar Concentration in Knockin Mice

BACKGROUND: Volatile anesthetics (VAs) alter the function of key central nervous system proteins but it is not clear which, if any, of these targets mediates the immobility produced by VAs in the face of noxious stimulation. A leading candidate is the glycine receptor, a ligand-gated ion channel imp...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Borghese, Cecilia M., Xiong, Wei, Oh, S. Irene, Ho, Angel, Mihic, S. John, Zhang, Li, Lovinger, David M., Homanics, Gregg E., Eger, Edmond I, Harris, R. Adron
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447119/
https://ncbi.nlm.nih.gov/pubmed/22885675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31826a0d93
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы