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Antithrombin III Toyama: replacement of arginine-47 by cysteine in hereditary abnormal antithrombin III that lacks heparin-binding ability.

Structural analyses of a hereditary abnormal antithrombin III, antithrombin III Toyama, which has normal progressive antithrombin activity but no heparin cofactor activity, have been carried out to elucidate the molecular abnormality causing recurrent thrombophlebitis of a patient and to identify an...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Koide, T, Odani, S, Takahashi, K, Ono, T, Sakuragawa, N
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1984
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344661/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6582486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.2.289
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