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Thromboembolic disease due to thermolabile conformational changes of antithrombin Rouen-VI (187 Asn-->Asp)

A new variant of antithrombin (Rouen-VI, 187 Asn-->Asp) with increased heparin affinity was shown to have normal inhibitory activity which decreased slowly at 4 degrees C and rapidly at 41 degrees C. On electrophoresis the freshly isolated variant had an anodal shift relative to native antithromb...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bruce, D, Perry, D J, Borg, J Y, Carrell, R W, Wardell, M R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1994
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC330053/
https://ncbi.nlm.nih.gov/pubmed/7989582
Etiketak: Etiketa erantsi
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