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Dissecting Quasi-Equivalence in Nonenveloped Viruses: Membrane Disruption Is Promoted by Lytic Peptides Released from Subunit Pentamers, Not Hexamers

Nonenveloped viruses often invade membranes by exposing hydrophobic or amphipathic peptides generated by a proteolytic maturation step that leaves a lytic peptide noncovalently associated with the viral capsid. Since multiple copies of the same protein form many nonenveloped virus capsids, it is unc...

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Main Authors: Domitrovic, Tatiana, Matsui, Tsutomu, Johnson, John E.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446560/
https://ncbi.nlm.nih.gov/pubmed/22761380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01089-12
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