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Small Compounds Targeted to Subunit Interfaces Arrest Maturation in a Nonenveloped, Icosahedral Animal Virus

Nudaurelia ω capensis virus (NωV) capsids were previously characterized in two morphological forms, a T=4, 485-Å-diameter round particle with large pores and a tightly sealed 395-Å icosahedrally shaped particle with the same quasi-symmetric surface lattice. The large particle converts to the smaller...

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Detalhes bibliográficos
Main Authors: Lee, Kelly K., Tang, Jinghua, Taylor, Derek, Bothner, Brian, Johnson, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC421682/
https://ncbi.nlm.nih.gov/pubmed/15194797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.13.7208-7216.2004
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