B-cell depletion therapy in patients with diffuse systemic sclerosis associates with a significant decrease in PDGFR expression and activation in spindle-like cells in the skin

INTRODUCTION: Recently, several studies assessing the clinical efficacy of rituximab (RTX) in systemic sclerosis (SSc) have reported encouraging results. We aimed at exploring whether RTX exerts its beneficial effects on fibrosis through attenuation of platelet-derived growth factor receptor (PDGFR)...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Daoussis, Dimitrios, Tsamandas, Athanassios C, Liossis, Stamatis-Nick C, Antonopoulos, Ioannis, Karatza, Elli, Yiannopoulos, Georgios, Andonopoulos, Andrew P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2012
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446529/
https://ncbi.nlm.nih.gov/pubmed/22697462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3879
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items