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Molecular abnormality of an inactive aldehyde dehydrogenase variant commonly found in Orientals.

Usual human livers contain two major aldehyde dehydrogenase [(ALDH) aldehyde:NAD+ oxidoreductase] isozymes--i.e., a cytosolic ALDH1 component and a mitochondrial ALDH2 component--whereas approximately equal to 50% of Orientals are "atypical" and have only the ALDH1 isozyme and are missing...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Yoshida, A, Huang, I Y, Ikawa, M
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1984
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344651/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6582480/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.1.258
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