Characterization of inhibitory T cells induced by an analog of type II collagen in an HLA-DR1 humanized mouse model of autoimmune arthritis

INTRODUCTION: We used DR1 transgenic mice and covalently linked DR1 multimers to characterize analog-specific inhibitory T cells in collagen-induced arthritis (CIA). Because of the low numbers of antigen-specific T cells in wild-type mice, functional T-cell studies in autoimmune arthritis have been...

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Hauptverfasser: Kimata, Masaru, Cullins, David L, Brown, Monica L, Brand, David D, Rosloniec, Edward F, Myers, Linda K, Stuart, John M, Kang, Andrew H
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446484/
https://ncbi.nlm.nih.gov/pubmed/22569209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3832
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