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T Cells Stimulated by an Analog Peptide of Type II Collagen Require FcRγ to Secrete IL-4 and Suppress Autoimmune Arthritis

OBJECTIVE: Using the collagen-induced arthritis (CIA) model, we explored the characteristics of the T cell population which responds to an analog peptide (A9) of type II collagen (CII) and regulates autoimmunity. METHODS: A9 is a 26 amino acid peptide analogous to the sequence of a segment of CII (C...

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Bibliographic Details
Main Authors: Myers, Linda K., Cullins, David L., Brand, David D., Kleinau, Sandra, Stuart, John M., Kang, Andrew H.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575180/
https://ncbi.nlm.nih.gov/pubmed/21590683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30454
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