Characterization of T cell phenotype and function in a double transgenic (collagen-specific TCR/HLA-DR1) humanized model of arthritis

INTRODUCTION: T cells orchestrate joint inflammation in rheumatoid arthritis (RA), yet they are difficult to study due to the small numbers of antigen-specific cells. The goal of this study was to characterize a new humanized model of autoimmune arthritis and to describe the phenotypic and functiona...

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Main Authors: Tang, Bo, Kim, Seunghyun, Hammond, Sarah, Cullins, David L, Brand, David D, Rosloniec, Edward F, Stuart, John M, Postlethwaite, Arnold E, Kang, Andrew H, Myers, Linda K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978884/
https://ncbi.nlm.nih.gov/pubmed/24405551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4433
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