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A molecular approach to leukemogenesis: mouse lymphomas contain an activated c-ras oncogene.

By inducing mouse thymomas with carcinogens and gamma-radiation, we have studied the potential of tumor DNA to induce foci in rodent fibroblasts. A high percentage of the tumors used transformed the cultured cells, and the oncogenic phenotype segregated with extra copies of the c-ras gene family. Th...

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Autors principals: Guerrero, I, Calzada, P, Mayer, A, Pellicer, A
Format: Artigo
Idioma:Inglês
Publicat: 1984
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC344639/
https://ncbi.nlm.nih.gov/pubmed/6582476
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