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A molecular approach to leukemogenesis: mouse lymphomas contain an activated c-ras oncogene.
By inducing mouse thymomas with carcinogens and gamma-radiation, we have studied the potential of tumor DNA to induce foci in rodent fibroblasts. A high percentage of the tumors used transformed the cultured cells, and the oncogenic phenotype segregated with extra copies of the c-ras gene family. Th...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1984
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344639/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6582476/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.1.202 |
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