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17beta-hydroxysteroid dehydrogenase type 1 modulates breast cancer protein profile and impacts cell migration

INTRODUCTION: Human 17beta-hydroxysteroid dehydrogenase type 1 (17β-HSD1) is a steroid-converting enzyme that has long been known to play critical roles in estradiol synthesis and more recently in dihydrotestosterone (DHT) inactivation, showing a dual function that promotes breast cancer cell prolif...

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Detalhes bibliográficos
Main Authors: Aka, Juliette A, Zerradi, Mouna, Houle, François, Huot, Jacques, Lin, Sheng-Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446355/
https://ncbi.nlm.nih.gov/pubmed/22691413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3207
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