High levels of RNA-editing site conservation amongst 15 laboratory mouse strains

BACKGROUND: Adenosine-to-inosine (A-to-I) editing is a site-selective post-transcriptional alteration of double-stranded RNA by ADAR deaminases that is crucial for homeostasis and development. Recently the Mouse Genomes Project generated genome sequences for 17 laboratory mouse strains and rich cata...

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Detalhes bibliográficos
Main Authors: Danecek, Petr, Nellåker, Christoffer, McIntyre, Rebecca E, Buendia-Buendia, Jorge E, Bumpstead, Suzannah, Ponting, Chris P, Flint, Jonathan, Durbin, Richard, Keane, Thomas M, Adams, David J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446300/
https://ncbi.nlm.nih.gov/pubmed/22524474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-4-r26
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