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Copy number variant detection in inbred strains from short read sequence data
Summary: We have developed an algorithm to detect copy number variants (CNVs) in homozygous organisms, such as inbred laboratory strains of mice, from short read sequence data. Our novel approach exploits the fact that inbred mice are homozygous at virtually every position in the genome to detect CN...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820678/ https://ncbi.nlm.nih.gov/pubmed/20022973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp693 |
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