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Increased expression but not sensitivity to Fas/CD95 in glioblastoma cells depleted of mitochondrial DNA

Mitochondria and Fas (CD95) play a role in tumorigenicity and apoptosis. In the present study, the functional relationship of mitochondria to Fas in mediating apoptosis was investigated. Glioblastoma cells (DBTRGO5MG, U87) were depleted of mitochondrial DNA (mtDNA) by treatment with ethidium bromide...

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Détails bibliographiques
Auteur principal: LIANG, BERTRAND C.
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445987/
https://ncbi.nlm.nih.gov/pubmed/22993639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2010.158
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