Interferon-γ Augments CD95(APO-1/Fas) and Pro-Caspase-8 Expression and Sensitizes Human Vascular Endothelial Cells to CD95-Mediated Apoptosis

We have examined the effects of interferon (IFN)-γ on expression and function of CD95 (APO-1/Fas) and associated proteins in cultured human umbilical vein and dermal microvascular endothelial cells (HUVEC and HDMEC, respectively). Unstimulated cells express only low levels of CD95; IFN-γ produces a...

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Main Authors: Li, Jie Hui, Kluger, Martin S., Madge, Lisa A., Zheng, Lian, Bothwell, Alfred L. M., Pober, Jordan S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867313/
https://ncbi.nlm.nih.gov/pubmed/12368221
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