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Increased expression but not sensitivity to Fas/CD95 in glioblastoma cells depleted of mitochondrial DNA

Mitochondria and Fas (CD95) play a role in tumorigenicity and apoptosis. In the present study, the functional relationship of mitochondria to Fas in mediating apoptosis was investigated. Glioblastoma cells (DBTRGO5MG, U87) were depleted of mitochondrial DNA (mtDNA) by treatment with ethidium bromide...

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Autore principale: LIANG, BERTRAND C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445987/
https://ncbi.nlm.nih.gov/pubmed/22993639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2010.158
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