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Collaboration of Kras and Androgen receptor signaling stimulates EZH2 expression and tumor propagating cells in prostate cancer

Elevation of the chromatin repression factor EZH2 is associated with progression and poor prognosis in several human cancers, including prostate cancer. However, the mechanisms driving EZH2 expression are not fully understood. In this study, we investigated the functional synergy in prostate cancers...

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Autors principals: Cai, Houjian, Memarzadeh, Sanaz, Stoyanova, Tanya, Beharry, Zanna, Kraft, Andrew S, Witte, Owen N.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445707/
https://ncbi.nlm.nih.gov/pubmed/22805308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0228
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