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Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal

The steroid hormone signaling axis is thought to play a central role in initiation and progression of many hormonally regulated epithelial tumors. It is unclear whether all cancer-initiating signals depend on an intact hormone receptor signaling machinery. To ascertain whether cell autonomous androg...

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Detalhes bibliográficos
Main Authors: Memarzadeh, Sanaz, Cai, Houjian, Janzen, Deanna M., Xin, Li, Lukacs, Rita, Riedinger, Mireille, Zong, Yang, DeGendt, Karel, Verhoeven, Guido, Huang, Jiaoti, Witte, Owen N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093518/
https://ncbi.nlm.nih.gov/pubmed/21518863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105243108
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