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Intramembrane charge movements and excitation– contraction coupling expressed by two-domain fragments of the Ca(2+) channel

To investigate the molecular basis of the voltage sensor that triggers excitation–contraction (EC) coupling, the four-domain pore subunit of the dihydropyridine receptor (DHPR) was cut in the cytoplasmic linker between domains II and III. cDNAs for the I-II domain (α1S 1–670) and the III-IV domain (...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Ahern, Chris A., Arikkath, Jyothi, Vallejo, Paola, Gurnett, Christina A., Powers, Patricia A., Campbell, Kevin P., Coronado, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34456/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11371610/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.111001898
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