Keratinocyte-Targeted Expression of Human Laminin γ2 Rescues Skin Blistering and Early Lethality of Laminin γ2 Deficient Mice

Laminin-332 is a heterotrimeric basement membrane component comprised of the α3, ß3, and γ2 laminin chains. Laminin-332 modulates epithelial cell processes, such as adhesion, migration, and differentiation and is prominent in many embryonic and adult tissues. In skin, laminin-332 is secreted by kera...

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Autores principales: Adair-Kirk, Tracy L., Griffin, Gail L., Meyer, Michelle J., Kelley, Diane G., Miner, Jeffrey H., Keene, Douglas R., Marinkovich, M. Peter, Ruppert, J. Michael, Uitto, Jouni, Senior, Robert M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445496/
https://ncbi.nlm.nih.gov/pubmed/23029085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045546
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