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Maintenance of Glomerular Filtration Barrier Integrity Requires Laminin α5

Mutation of the mouse laminin α5 gene results in a variety of developmental defects, including defects in kidney structure and function. Whereas the total absence of laminin α5 results in breakdown of the glomerular basement membrane (GBM) and failed glomerular vascularization, a hypomorphic Lama5 m...

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Detalhes bibliográficos
Main Authors: Goldberg, Seth, Adair-Kirk, Tracy L., Senior, Robert M., Miner, Jeffrey H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844312/
https://ncbi.nlm.nih.gov/pubmed/20150535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009091004
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