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Maintenance of Glomerular Filtration Barrier Integrity Requires Laminin α5
Mutation of the mouse laminin α5 gene results in a variety of developmental defects, including defects in kidney structure and function. Whereas the total absence of laminin α5 results in breakdown of the glomerular basement membrane (GBM) and failed glomerular vascularization, a hypomorphic Lama5 m...
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Main Authors: | , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Society of Nephrology
2010
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844312/ https://ncbi.nlm.nih.gov/pubmed/20150535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009091004 |
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