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Caspase 2 Activation and ER Stress Drive Rapid Jurkat Cell Apoptosis by Clofibrate

Differently from the antiapoptotic action most commonly assigned to peroxisome proliferators (PPs), we demonstrated that some of them, clofibrate (CF) in particular, display clearcut apoptogenic properties on rat hepatoma cell lines. We and others could confirm that CF as well as various other PPs c...

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Main Authors: Penna, Fabio, Pin, Fabrizio, Costamagna, Domiziana, Reffo, Patrizia, Baccino, Francesco Maria, Bonelli, Gabriella, Costelli, Paola
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445471/
https://ncbi.nlm.nih.gov/pubmed/23028936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045327
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