Caspase 2 Activation and ER Stress Drive Rapid Jurkat Cell Apoptosis by Clofibrate

Differently from the antiapoptotic action most commonly assigned to peroxisome proliferators (PPs), we demonstrated that some of them, clofibrate (CF) in particular, display clearcut apoptogenic properties on rat hepatoma cell lines. We and others could confirm that CF as well as various other PPs c...

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Bibliografske podrobnosti
Main Authors: Penna, Fabio, Pin, Fabrizio, Costamagna, Domiziana, Reffo, Patrizia, Baccino, Francesco Maria, Bonelli, Gabriella, Costelli, Paola
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445471/
https://ncbi.nlm.nih.gov/pubmed/23028936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045327
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