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The P granule component PGL-1 promotes the localization and silencing activity of the PUF protein FBF-2 in germline stem cells
In the C. elegans germline, maintenance of undifferentiated stem cells depends on the PUF family RNA-binding proteins FBF-1 and FBF-2. FBF-1 and FBF-2 are 89% identical and are required redundantly to silence the expression of mRNAs that promote meiosis. Here we show that, despite their extensive se...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Company of Biologists
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3445306/ https://ncbi.nlm.nih.gov/pubmed/22991439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.083980 |
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