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The C. elegans homolog of nucleoporin Nup98 is required for the integrity and function of germline P granules

C. elegans P granules are conserved cytoplasmic ribonucleoprotein complexes that are unique to the germline and essential for fertility. During most of germline development, P granules are perinuclear and associate with clusters of nuclear pores. In an RNAi screen against nucleoporins, we have ident...

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Библиографические подробности
Главные авторы: Voronina, Ekaterina, Seydoux, Geraldine
Формат: Artigo
Язык:Inglês
Опубликовано: Company of Biologists 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853846/
https://ncbi.nlm.nih.gov/pubmed/20335358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.047654
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